Pineal tumors originate from normal cells in the pineal gland. The pineal gland is located in the center of the brain and is involved in the secretion of specific hormones.
Tumor types occurring in the pineal region may or may not involve the pineal gland. True pineal cell tumors—pineocytoma, pineoblastoma, and mixed pineal tumors—are covered on this page.
Tumors that may occur in this region but are not necessarily pineal tumors include: germinoma, non-germinoma (eg, teratoma, endodermal sinus tumor, embryonal cell tumor, choriocarcinoma, and mixed tumors), meningioma, astrocytoma, ganglioglioma, and dermoid cysts. Information on these particular tumors can be found elsewhere on this site.
There are three types of pineal tumors:
- Pineocytoma: Slow-growing, grade II tumor.
- Pineoblastoma: More aggressive, grade IV, malignant (cancerous) tumor. A grade III intermediate form has also been described.
- Mixed Pineal Tumor: Contains a combination of cell types.
Location
Symptoms
Treatment
Standard treatment for these kinds of tumors is radiation therapy. Radiation of the entire brain and spinal cord is recommended in patients with pineoblastoma. Chemotherapy may also be considered, particularly if the tumor has spread or if it regrows.
Surgery may be possible in some individuals to determine the tumor type and remove part of the tumor. In some cases, placement of a shunt (similar to a drain) is used to relieve pressure caused by buildup of cerebrospinal fluid.
Incidence
Additional Resources
Content last reviewed:
May 2018