Choroid Plexus

Choroid Plexus

These tumors arise from brain tissue called the “choroid plexus.” They commonly invade nearby tissue and spread widely via the cerebrospinal fluid.

Like other brain tumors, choroid plexus tumors are also “graded.” Choroid plexus papilloma are grade I tumors. Atypical choroid plexus papillomas are considered grade II, and chroid plexus carcinomas are typically grade III tumors.

Location:

These tumors arise from the choroid plexus, which lines the ventricles of the brain and produces cerebrospinal fluid.

Lateral and third ventricle tumors tend to be found in very young children. Fourth ventricle and cerebellopontine angle tumors (the angle between the cerebrum and the pons of the brain stem) generally occur in patients ages 20-35.

Choroid plexus papilloma is a rare, benign (noncancerous) tumor. Choroid plexus carcinoma is the malignant (cancerous) form of the choroid plexus papilloma. Choroid plexus carcinoma occurs primarily in children.

Symptoms:

Headache and other symptoms of increased pressure in the brain are common.

Treatment:

Surgery may be the only treatment required if the tumor is completely removed. Tumor removal relieves the hydrocephalus (excess water in the brain) about half of the time. A shunt (drainage system) may be required for other patients.

The role of radiation or chemotherapy in the treatment of choroid plexus tumors is still being defined. It may be recommended for patients with tumors that are either not completely removed or not removable. A second surgery might be recommended for recurrent tumors, followed by some form of radiation and/or chemotherapy.

Incidence:

This group of tumors comprise about 10-20% of all brain tumors diagnosed in children during their first year of life. They represent 2-4% of tumors found in children under age 15.

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Mindee Plugues

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Mindee J. Plugues, of Los Angeles, CA, is vice president, marketing for the Applebee’s brand and brings skills including brand strategy, executive leadership, and marketing to the board. Plugues has been an ABTA donor since April 2001, following her father’s passing from GBM. She is also a former member of the ABTA endurance program, Team Breakthrough.

Bob Kruchten

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Bob Kruchten, of Mount Prospect, IL, is a sales manager at Extreme Reach, a leading advertising technology company. He has strong skills in communications and fundraising, and has been advocating for the ABTA for 19 years in tribute to his best friend, Paul Fabbri, who lost his 10-year battle with GBM in 1998. Kruchten accepted the ABTA’s Joel A. Gingras Jr. Award in 2015 on behalf of the Paul Fabbri Memorial Fund.