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Brain Tumor Treatment Centers

Northwestern Memorial Hospital

Lou and Jean Malnati Brain Tumor Institute

675 North Saint Clair Street, Chicago, Illinois, 60611, United States

Phone number:

312-695-4360

Street address:

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Website:

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Additional Information:

This program meets 7/7 of the Guiding Principles for CNS Tumor Treatment Programs.

Institution part of Northwestern Medicine.

Awards/Certifications:

  • US News World Report Hospital #6 for Neurology/Neurosurgery and Cancer Care
  • Ranked “Exceptional” by the National Cancer Institute (NCI)
  • One of 6 programs in the country with a brain tumor SPORE award

Data for this institution collected in 2025.

Accreditations:

  • National Cancer Institute Designation: Yes
  • Nurse Magnet Status: Yes
  • Academic Affiliation: Northwestern University Feinberg School of Medicine

Number of Full-Time Physicians:

Number of full-time physicians in this treatment program who dedicate at least 40% of their clinical practice to the treatment of adult patients diagnosed with brain and/or spine tumors:
  • 8 Neuro-oncologists or Medical Oncologists specializing in brain/spine tumors
  • 10 Brain Neurosurgeons
  • 2 Spine Neurosurgeons
  • 7 Radiation Oncologists
  • 5 Neuropathologists

Number of Adult Patients Treated for Brain and/or Spine Tumors Annually:

  • ~2250 Primary tumor patients
  • ~700 Metastatic (Secondary) tumor patients

Number of Adult Patients Treated with Surgery Annually:

  • 605 Primary brain tumor patients
  • 166 Metastatic (Secondary) brain tumor patients
  • 36 Primary spine tumor patients
  • 10 Metastatic (Secondary) spine tumor patients
  • 120 Skull base tumor patients

Specialized Treatments and Technologies Available:

Identifies whether the following treatment options are offered either at this institution or at an affiliated center.

Available:

Drug:

  • Immunotherapy
  • Intrathecal chemotherapy
  • Targeted therapy

Imaging Treatments and Technologies:

  • fMRI
  • MRI Spectroscopy
  • MRI Tractography
  • Perfusion MRI
  • Positron Emission Tomography (PET)

Other:

  • EEG
  • Tumor treating fields (TTF)

Radiation Treatments and Technologies:

  • 3D Conformal Radiation Therapy (3D-CRT)
  • Hippocampal avoidance (for WBRT)
  • Intensity Modulated Radiation Therapy (IMRT)
  • Intraoperative radiotherapy
  • Proton Therapy
  • Stereotactic Radiosurgery

Surgical Treatments and Technologies:

  • Awake Craniotomy
  • Brain Mapping
  • Endoscopic Surgery
  • Fluorescence-guided surgery
  • Intraoperative MRI
  • Laser Interstitial Thermal Therapy (LITT)
  • Minimally Invasive Surgery

Clinical Trials:

Investigational treatments (or other interventions) available for the categories below:
  • Low Grade Glioma
  • Meningioma
  • Metastatic Brain Tumors
  • Newly Diagnosed Glioblastoma
  • Other Malignant Glioma
  • Recurrent Glioblastoma

Other:

  • CNS lymphoma

Support Services Available:

Identifies whether the following clinical and non-clinical support services are offered either at this institution or at an affiliated center.

Available:

  • Advanced practice registered nurse
  • Brain tumor board
  • Brain tumor support group
  • Caregiver support services
  • Case manager
  • CNS tumor educational resources
  • Discounted lodging
  • Fellowship-trained neuro-oncologist
  • Financial aid services
  • Inpatient rehabilitation
  • Molecular testing
  • Neurological Intensive Care Unit (Neuro ICU)
  • Neuropsychology services for CNS tumor patients
  • Nurse Navigator
  • Oncology social worker
  • Outpatient Rehabilitation
  • Palliative care
  • Survivorship services
  • Transportation services
  • Virtual second opinion service

Other:

  • Specialty clinics:
    • Paraneoplastic syndromes
    • Low grade glioma program
    • von Hippel-Lindau disease (VHL)
    • Meningioma

Last updated July 29, 2025