Research Funding Impact

2019: WHERE THE MONEY GOES

Guided by our mission, and advised by a multidisciplinary team of experts, the ABTA is dedicated to funding research that has the potential to change the lives of people affected by brain tumors. We also aim to “seed the field” with promising up-and-coming researchers in the brain tumor space.

  • The ABTA awarded $1.265 million in grants to 21 new projects
    • $200,000 funded 1 Research Collaboration Grant
    • $600,000 funded 6 Basic Research Fellowships
    • $450,000 funded 9 Discovery Grants
    • $15,000 funded 5 Medical Student Summer Fellowship Grants
  • These grants funded projects spanning across multiple tumor types:
    • Anaplastic oligodendroglioma, Chordoma, Choroid plexus carcinoma, Diffuse intrinsic pontine glioma, Glioblastoma, Low grade gliomas, Malignant gliomas, Medulloblastoma, Metastatic Tumors
  • Research areas of focus:
    • Apoptosis/Cell Death, Biomarkers, Cell Cycle, Cell Signaling, Cellular Differentiation or Transformation, Drug Therapies/Experimental Therapeutics, Genetics, Immunotherapy/Immunology, Invasion/motility, Neuropathology/Classification Systems, Stem Cells

2020: CURRENTLY FUNDED RESEARCHERS

Research Collaboration Grant

The ABTA Research Collaboration Grant is a two-year grant that supports a multi-PI, multidisciplinary project that can accelerate advances in the understanding and treatment of brain tumors through collaborative team science.

See the Newly Awarded 2019 – 2021 Grantees

Justin Lathia, PhD

 

Grant: Research Collaboration Grant

Institute: Cleveland Clinic

Co-Pl: Joshua Rubin, MD, PhD

Co-Pl Institute: Washington University in St. Louis

Project: Identifying Sex Differences in Intrinsic and Extrinsic Mechanisms in GBM

Tribute: In memory of Victor Perez Maldonado

See the 2018 – 2020 Grantees

Anderson Persson, PhD

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Institute: University of California, San Francisco

Co-Pl: Andrew Chi, MD, PhD

Co-Pl Institute: New York University School of Medicine

Project: Synthetic lethal targeting of NAD(P)H-dependent DNA damage in IDH mutant gliomas

Tribute: Supported by Humor to Fight the Tumor

Basic Research Fellowship

The ABTA Basic Research Fellowship is a two-year mentored grant supporting postdoctoral fellows who are conducting laboratory or field-based research projects that focus on brain tumors.

See the Newly Awarded 2019 – 2021 Grantees

Javier Ganz, PhD

View research project summary

Grant: Basic Research Fellowship

Institute: Children’s Hospital Boston

Mentor: Christopher A. Walsh, MD, PhD

Project: Precancer Mutations in Normal Brain: Implications for Oncogenesis and Diagnosis

Tribute: In honor of Joel A. Gingras, Jr.


 

Maria Garcia Fabiani, PhD

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Grant: Basic Research Fellowship

Institute: University of Michigan

Mentor: Maria Castro, PhD

Project: Impact of H3G34R Mutation in Reprogramming the Glioma Immune Microenvironment

Tribute: In memory of Bruce and Brian Jackson


 

Albert Kim, MD

View research project summary

Grant: Basic Research Fellowship

Institute: Massachusetts General Hospital

Mentor: Elizabeth Gerstner, MD

Project: Noninvasive Tools to Study Brain Metastasis Resistance to Immunotherapy

Tribute: In honor of Paul Fabbri


Thi Thu Trang Nguyen, PhD

View research project summary

Grant: Basic Research Fellowship

Institute: Columbia University

Mentor: Markus Siegelin, MD

Project: LXR Agonists Combined with BH3-Mimetics as a Novel Treatment for Glioblastoma

Tribute: In memory of Katie Monson


Jan Remsik, PharmD, PhD

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Grant: Basic Research Fellowship

Institute: Memorial Sloan-Kettering Cancer Center

Mentor: Adrienne Boire, MD, PhD

                        Project: Immunological determinants of metastatic                                    colonization of leptomeninges

                                         Tribute: Supported by an Anonymous Corporate Partner


 

Anh Tran, PhD

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Grant: Basic Research Fellowship

Institute: Northwestern University

Mentor: Craig Horbinski, MD, PhD

Project: Tissue Factor as a Regulator of Receptor Tyrosine Kinases in Glioblastoma

Tribute: In honor of Ned Smith and Team Smith Strong

Discovery Grant

The ABTA Discovery Grant is a one-year grant for high risk, high impact research with the potential to change current diagnostic or treatment models.

See the Newly Awarded 2019 Grantees

Maryam Rahman, MD, MS, FAANS

View research project summary

Grant: Discovery Grant

Institute: University of Florida

Project: A Vaccine Strategy to Overcome Treatment Induced Immunosuppression in Glioma

Tribute: Supported by Southeastern Brain Tumor Foundation


Lohitash Karumbaiah, PhD

View research project summary

Grant: Discovery Grant

Institute: University of Georgia

Project: Immunosensing Glioblastoma Induced Glycomodulation

Tribute: Supported by Uncle Kory Foundation


Christian Badr, PHD

View research project summary

Grant: Discovery Grant

Institute: Massachusetts General Hospital

Project: Therapeutic Targeting of Endoplasmic Reticulum Proteostasis in GBM

Tribute: Supported by Uncle Kory Foundation


Yiping He, PhD

View research project summary

Grant: Discovery Grant

Institute: Duke University Medical Center

Project: Repurposing Remyelination Drugs for Oligodendroglioma Therapeutics

Tribute: Supported by an Anonymous Family Foundation


 

Wen Jiang, MD, PhD

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Grant: Discovery Grant

Institute: University of Texas Southwestern Medical Center

Mentor: Robert Bachoo, MD, PhD

Project: Bridging Innate and Adaptive GBM Immunity via Phagocytosis Checkpoint Blockade

Tribute: Supported by an Anonymous Family Foundation


 

Christine O’Connor, PhD

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Grant: Discovery Grant

Institute: Cleveland Clinic

Mentor: Justin Lathia, PhD

Project: Cytomegalovirus Oncomodulation of the Glioblastoma Tumor Environment

Tribute: In memory of George Surgent


 

Min Tang-Schomer, PhD

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Grant: Discovery Grant

Institute: The Jackson Laboratory for Genomic Medicine

Mentor: Ching Lau, MD, PhD

Project: Microcircuit Platform to Screen                                      Channel Blockers for Medulloblastoma

      Tribute: Supported by an Anonymous Family                                      Foundation


 

Lee Wong, PhD

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Grant: Discovery Grant

Institute: Monash University

Project: An Investigation of Telomere Maintenance Mechanism in ATRX Mutant Gliomas

Tribute: Supported by The Bradley Benton Davis Foundation


 

Zeng-jie Yang, MD, PhD

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Grant: Discovery Grant

Institute: The Research Institute of Fox Chase Cancer Center

Project: NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma

Tribute: Supported by an Anonymous Family Foundation

Jack & Fay Netchin Medical Student Summer Fellowship

The ABTA Medical Student Summer Fellowship program is a 10-12 week mentor-guided summer research experience, intended to motivate talented medical students to pursue a career in neuro-oncology research.

See Newly Awarded 2020 Grantees

 

Hasan Alrefai, BS

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Institute: University of Alabama at Birmingham

Mentor: Christopher Willey, MD, PhD

Project: Effects of Myristoylated Alanine-Rich C-Kinase Substrate on Microglial Activation

Tribute: In memory of George Surgent

 


 

Ian Burns

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Institution: McMaster University

Mentor: Sheila Singh, MD, PhD, FRCS(C), FAANS 

Project: Identifying Synergistic Therapies for Pediatric Group 3 Medulloblastoma

Tribute: In honor of Davvy Lila Netchin


 

 

Andy Ding, BA

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Institution: Johns Hopkins University School of Medicine

Mentor: Henry Brem, MD

Project: Therapeutic Potential of Multi-CDK Inhibition in Atypical Teratoid/Rhabdoid Tumor

Tribute: In honor of Paul Fabbri

 


 

Emily Lavell, MHS

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Institution: Mayo Clinic in Jacksonville, Florida

Mentor: Hugo Guerrero-Cazares, MD, PhD

Project:  Role of Glioma Extracellular Vesicles on the Transformation of Neural Stem Cells

Tribute:  Supported by Southeastern Brain Tumor Foundation


 

Brian V. Lien, MS

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Institution: University of California Irvine School of
Medicine

Mentor: Daniel Lim, MD, PhD

Project: Dissecting the Molecular Mechanism of lncGRS-1 in Glioblastoma

Tribute: In memory of Katie Monson


 

Edith Yuan, BA

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Institution: Keck School of Medicine – University of Southern California

Mentor: Frank Attenello, MD

Project: Effects of Silencing Long Non-Coding RNA on the Malignancy of Glioblastomas

Tribute: In memory of Rose DiGangi