Research Funding Impact

2019: WHERE THE MONEY GOES

Guided by our mission, and advised by a multidisciplinary team of experts, the ABTA is dedicated to funding research that has the potential to change the lives of people affected by brain tumors. We also aim to “seed the field” with promising up-and-coming researchers in the brain tumor space.

  • The ABTA awarded $1.115 million in grants to 18 new projects
    • $200,000 funded 1 Research Collaboration Grant
    • $600,000 funded 6 Basic Research Fellowships
    • $300,000 funded 6 Discovery Grants
    • $15,000 funded 5 Medical Student Summer Fellowship Grants
  • These grants funded projects spanning across multiple tumor types:
    • Anaplastic oligodendroglioma, Chordoma, Choroid plexus carcinoma, Diffuse intrinsic pontine glioma, Glioblastoma, Low grade gliomas, Malignant gliomas, Medulloblastoma, Metastatic Tumors
  • Research areas of focus:
    • Apoptosis/Cell Death, Biomarkers, Cell Cycle, Cell Signaling, Cellular Differentiation or Transformation, Drug Therapies/Experimental Therapeutics, Genetics, Immunotherapy/Immunology, Invasion/motility, Neuropathology/Classification Systems, Stem Cells

2019: CURRENTLY FUNDED RESEARCHERS

Research Collaboration Grant

The ABTA Research Collaboration Grant is a two-year grant that supports a multi-PI, multidisciplinary project that can accelerate advances in the understanding and treatment of brain tumors through collaborative team science.

See the Newly Awarded 2019 – 2021 Grantees

Justin Lathia, PhD

Grant: Research Collaboration Grant Institute: Cleveland Clinic Co-Pl: Joshua Rubin, MD, PhD Co-Pl Institute: Washington University in St. Louis Project: Identifying Sex Differences in Intrinsic and Extrinsic Mechanisms in GBM

See the 2018 – 2020 Grantees

Anders Persson, PhD

View research project summary Institute: University of California, San Francisco Co-Pl: Andrew Chi, MD, PhD Co-Pl Institute: New York University School of Medicine Project: Synthetic lethal targeting of NAD(P)H-dependent DNA damage in IDH mutant gliomas Tribute: Supported by Humor to Fight the Tumor

Basic Research Fellowship

The ABTA Basic Research Fellowship is a two-year mentored grant supporting postdoctoral fellows who are conducting laboratory or field-based research projects that focus on brain tumors.

See the Newly Awarded 2019 – 2021 Grantees

Javier Ganz, PhD

View research project summary Grant: Basic Research Fellowship Institute: Children’s Hospital Boston Mentor: Christopher A. Walsh, MD, PhD Project: Precancer Mutations in Normal Brain: Implications for Oncogenesis and Diagnosis

Maria Garcia Fabiani, PhD

View research project summary Grant: Basic Research Fellowship Institute: University of Michigan Mentor: Maria Castro, PhD Project: Impact of H3G34R Mutation in Reprogramming the Glioma Immune Microenvironment

Albert Kim, MD

View research project summary Grant: Basic Research Fellowship Institute: Massachusetts General Hospital Mentor: Elizabeth Gerstner, MD Project: Noninvasive Tools to Study Brain Metastasis Resistance to Immunotherapy

Thi Thu Trang Nguyen, PhD

View research project summary Grant: Basic Research Fellowship Institute: Columbia University Mentor: Markus Siegelin, MD Project: LXR Agonists Combined with BH3-Mimetics as a Novel Treatment for Glioblastoma

Jan Remsik, PharmD, PhD

View research project summary Grant: Basic Research Fellowship Institute: Memorial Sloan-Kettering Cancer Center Mentor: Adrienne Boire, MD, PhD Project: Immunological determinants of metastatic colonization of leptomeninges

Anh Tran, PhD

View research project summary Grant: Basic Research Fellowship Institute: Northwestern University Mentor: Craig Horbinski, MD, PhD Project: Tissue Factor as a Regulator of Receptor Tyrosine Kinases in Glioblastoma ​

Discovery Grant

The ABTA Discovery Grant is a one-year grant for high risk, high impact research with the potential to change current diagnostic or treatment models.

See the Newly Awarded 2019 Grantees

Yiping He, PhD

View research project summary Grant: Discovery Grant Institute: Duke University Medical Center Project: Repurposing Remyelination Drugs for Oligodendroglioma Therapeutics

Wen Jiang, MD, PhD

View research project summary Grant: Discovery Grant Institute: University of Texas Southwestern Medical Center Mentor: Robert Bachoo, MD, PhD Project: Bridging Innate and Adaptive GBM Immunity via Phagocytosis Checkpoint Blockade

Christine O’Connor, PhD

View research project summary Grant: Discovery Grant Institute: Cleveland Clinic Mentor: Justin Lathia, PhD Project: Cytomegalovirus Oncomodulation of the Glioblastoma Tumor Environment

Min Tang-Schomer, PhD

View research project summary Grant: Discovery Grant Institute: The Jackson Laboratory for Genomic Medicine Mentor: Ching Lau, MD, PhD Project: Microcircuit Platform to Screen Ion Channel Blockers for Medulloblastoma

Lee Wong, PhD

View research project summary Grant: Discovery Grant Institute: Monash University Project: An Investigation of Telomere Maintenance Mechanism in ATRX Mutant Gliomas

Zeng-jie Yang, MD, PhD

View research project summary Grant: Discovery Grant Institute: The Research Institute of Fox Chase Cancer Center Project: NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma

Medical Student Summer Fellowship

The ABTA Medical Student Summer Fellowship program is a 10-12 week mentor-focused summer program, intended to motivate talented medical students to pursue a career in neuro-oncology research.

See the Newly Awarded Summer Fellows

Nyle Almeida, BS

View project summary Institute: University of California, San Francisco Mentor: Shawn Hervey-Jumper, MD Project: Synaptogenic Glioma Cell Enrichment in High Connectivity Regions of Adult Glioma

Sakibul Huq, BS

View project summary Institute: Johns Hopkins University School of Medicine Mentor: Henry Brem, MD Project: Identification of EZH2 and elf4E as New Therapeutic Targets in Chordoma

Joshi-Photo

Rushikesh Joshi, BS

View project summary Institute: University of California, San Francisco Mentor: Manish Aghi, MD Project: Identifying Mediators of Perivascular Invasion in Glioblastoma

Shoeb Lallani, BS

View project summary Institute: The University of Alabama at Birmingham Mentor: Anita Hjelmeland, PhD Project: Defining a Role for the GCH1/BH4 pathway in Brain Tumor Therapeutic Resistance

Melanie Schweitzer, BS

View project summary Institute: New York Institute of Technology Mentor: Haotian Zhao, PhD Project: Notch-Targeted Therapy for Choroid Plexus Carcinoma
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Mindee Plugues

Member

Mindee J. Plugues, of Los Angeles, CA, is vice president, marketing for the Applebee’s brand and brings skills including brand strategy, executive leadership, and marketing to the board. Plugues has been an ABTA donor since April 2001, following her father’s passing from GBM. She is also a former member of the ABTA endurance program, Team Breakthrough.

Bob Kruchten

Member

Bob Kruchten, of Mount Prospect, IL, is a sales manager at Extreme Reach, a leading advertising technology company. He has strong skills in communications and fundraising, and has been advocating for the ABTA for 19 years in tribute to his best friend, Paul Fabbri, who lost his 10-year battle with GBM in 1998. Kruchten accepted the ABTA’s Joel A. Gingras Jr. Award in 2015 on behalf of the Paul Fabbri Memorial Fund.