Choroid Plexus

  • SHARE
  • EmailFacebookTwitter
    Share on Facebook
    Cancel
    Share on MySpace
    Cancel
    Share on Twitter
    A short URL will be added to the end of your Tweet.

    Cancel
    Share on LinkedIn
    Cancel
Printer Friendly

These tumors arise from brain tissue called the “choroid plexus.” They commonly invade nearby tissue and spread widely via the cerebrospinal fluid.

 

Choroid plexus papilloma is a rare, benign (noncancerous) tumor. Choroid plexus carcinoma is the malignant (cancerous) form of the choroid plexus papilloma. Choroid plexus carcinoma occurs primarily in children.

 

Location

These tumors arise from the choroid plexus, which lines the ventricles of the brain and produces cerebrospinal fluid.

 

Lateral and third ventricle tumors tend to be found in very young children. Fourth ventricle and cerebellopontine angle tumors (the angle between the cerebrum and the pons of the brain stem) generally occur in patients ages 20-35.

 

Description

Like other brain tumors, choroid plexus tumors are also “graded.” Choroid plexus papilloma are grade I tumors. Atypical choroid plexus papillomas are considered grade II, and chroid plexus papillomas are typically grade III tumors.

 

Symptoms

Headache and other symptoms of increased pressure in the brain are common.

 

Incidence

This group of tumors comprise about 10-20% of all brain tumors diagnosed in children during their first year of life. They represent 2-4% of tumors found in children under age 15.

 

Cause

Like many other types, the exact cause of choroid plexus tumors is not known.

 

Treatment

Surgery may be the only treatment required if the tumor is completely removed. Tumor removal relieves the hydrocephalus (excess water in the brain) about half of the time. A shunt (drainage system) may be required for other patients.

 

The role of radiation or chemotherapy in the treatment of choroid plexus tumors is still being defined. It may be recommended for patients with tumors that are either not completely removed or not removable. A second surgery might be recommended for recurrent tumors, followed by some form of radiation and/or chemotherapy.

 

Learn more about different treatment options for brain tumors on our Treatment page.

 

New approaches to treatment are currently in development. These new therapies are offered in organized research studies called clinical trials. Click here to access TrialConnect®, the ABTA's clinical trial match service.