Researchers at John Hopkins have concluded that the link between brain cancers and cytomegalovirus (CMV) likely does not exist. Since 2002, there have been several studies have been conducted on tumor cells in glioblastoma (GBM) and other gliomas that suggested they were infected by CMV. However, this data contradicts those previous studies. CMV is a herpes virus that infects more than 50% of all adults by the age of 40, and is in the same family as viruses that cause chickenpox and mononucleosis.
The researchers chose to use an “exhaustive” study design which means that CMV was tested for in these tumors using multiple techniques. The study tested 99 adult and 26 pediatric GBM and other high-grade gliomas. A lot of time and resources have already gone into potentially targeting CMV, so researchers are eager to find a definitive answer.
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