Brain Tumor Cells Will Shrink, Die without Cholesterol, Study Finds

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October 18, 2016

In a recent study at the University of California San Diego School of Medicine, Professor Paul Mischel noted that when they deprived brain tumors, specifically glioblastomas, of cholesterol, this would cause tumor cells to die off and the tumor to regress. In previous studies, the scientists noted that GBM cells could not create their own cholesterol and would have to receive this vital component of its structure from normal astrocytes.
 

Glioblastoma (GBM) is the most common and more aggressive type of brain tumor. An average life span with a GBM diagnosis is 14 months. If the tumor cells are killed and the tumor is shrunk, this could increase a patient’s life expectancy. With the success of this study, Professor Mischel suggested that this strategy could be implemented in clinical trials.
 

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