A hint of increased brain tumor risk—five years before diagnosis

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September 10, 2015

According to a new study published in PLOS ONE, using blood samples collected, over an average of 15 years before a brain tumor diagnosis, researchers analyzed the relationships among 12 allergy-related proteins. Researchers at The Ohio State University looked at how those relationships were different between people later diagnosed with brain tumors and cancer-free groups.

Study findings suggest that changes in immune function can occur as long as five years before the diagnosis of a brain tumor, which typically produces symptoms approximately three months before it is detected.

For this study, blood samples were collected from Janus Serum Bank in Norway. Researchers analyzed cytokines in the blood samples of 487 people diagnosed with a glioma (315 people had a GBM) compared to 487 people without a brain tumor. Blood samples had been taken on average of 15 years before those who developed tumors received the diagnosis.

Lead author of the study, Judith Schwartzbaum, said “Now, clinicians don't have any way to detect the tumors until patients have symptoms, which is typically three months before diagnosis. I see something five years before." Dr. Schwartzbaum is an associate professor of epidemiology at The Ohio State University.

This story was published by Medicaxpress.com on Sept 9, 2015. Read more about this study online